Australian pharmaceutical research company Pharmaxis has teamed up with the University of Western Australia (UWA) to start a world-first clinical trial to investigate a cream to stop scars forming after trauma, particularly following burn injuries.

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Australian pharmaceutical research company Pharmaxis has teamed up with the University of Western Australia (UWA) to start a world-first clinical trial to investigate a cream to stop scars forming after trauma, particularly following burn injuries.

The trial will be led by prominent surgeon and burns expert Professor Fiona Wood and her team from UWA and researchers from Fiona Stanley Hospital in Murdoch, Western Australia.

Together they will test Pharmaxis’s topical discovery, known as PXS-6302, which has shown promising pre-clinical results in restraining the enzymes that play a significant role in the development of scar tissue.

 “It’s exciting for the research team to explore a novel path to reduce scarring and to be moving closer to that goal,” said Professor Fiona Wood.

“Scar-less healing is the vision that has motivated our work over many decades.”

 “Current treatments aim to rectify the scar in the acute phase such as during wound healing and scar maturation through options such as compression therapy, silicone gel sheeting or when the scar is established by cryotherapy, scar revision or laser, with limited outcomes at times,” said senior research fellow at UWA’s School of Biomedical Sciences Dr Kylie Sandy-Hodgetts.

“This new compound may potentially avoid the need for invasive procedures such as further surgery or laser procedures.”

The pioneering human trial will first evaluate the safety and tolerability of the product in healthy volunteers before conducting further trials in burns and surgical patients.

Pharmaxis to start world-first trial of scar-reducing wound treatment

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